A sleek white pump bottle of r-Retinoate Day & Night stands upright, with a swirl of white cream next to it.
A woman's face is shown with a small amount of white cream on their cheek. Four bullet points with checkmarks list benefits: Visibly brightens, revitalises & smooths the skin; For results 8x more powerful than retinol* – both day & night; Improves uneven skin tone & texture; and a 3-in-1 serum for a simplified regime.
A display showcasing THE R-RETINOATE RANGE. It includes, r-RETINOATE DAY & NIGHT EYE SERUM, r-RETINOATE DAY & NIGHT, r-RETINOATE INTENSE. All bottles feature PATENTED TECHNOLOGY.
A HOW TO LAYER diagram for skincare routines. The AM routine includes Cleanse (Surface Radiance Cleanse), Tone (Press & Glow), Vitamin C + Vitamin A (r-Retinoate Day & Night), and Sunscreen (Advanced Day Total Protect). The PM routine involves Cleanse (Lipid-Balance Cleansing Oil), Tone (Press & Clear), Vitamin C + Vitamin A (r-Retinoate Day & Night), and Moisturise (Advanced Night Restore).
A sleek white pump bottle of r-Retinoate Day & Night stands beside its matching white carton
A sleek white pump bottle of r-Retinoate Day & Night stands upright, with a swirl of white cream next to it.
A woman's face is shown with a small amount of white cream on their cheek. Four bullet points with checkmarks list benefits: Visibly brightens, revitalises & smooths the skin; For results 8x more powerful than retinol* – both day & night; Improves uneven skin tone & texture; and a 3-in-1 serum for a simplified regime.
A display showcasing THE R-RETINOATE RANGE. It includes, r-RETINOATE DAY & NIGHT EYE SERUM, r-RETINOATE DAY & NIGHT, r-RETINOATE INTENSE. All bottles feature PATENTED TECHNOLOGY.
A HOW TO LAYER diagram for skincare routines. The AM routine includes Cleanse (Surface Radiance Cleanse), Tone (Press & Glow), Vitamin C + Vitamin A (r-Retinoate Day & Night), and Sunscreen (Advanced Day Total Protect). The PM routine involves Cleanse (Lipid-Balance Cleansing Oil), Tone (Press & Clear), Vitamin C + Vitamin A (r-Retinoate Day & Night), and Moisturise (Advanced Night Restore).
A sleek white pump bottle of r-Retinoate Day & Night stands beside its matching white carton
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Fine Lines & Wrinkles

r-Retinoate® Day & Night

  • Brighten
  • |
  • Smooth
  • |
  • Revive
Youth Activating Cream

Our remarkable vitamin A that can be used both day and night for faster visible brightening, revitalising and smoothing results while remaining gentle.

This luxurious serum is powered by Medik8-exclusive encapsulated retinyl retinoate - proven to be 8x more powerful than standard retinol* in delivering age-defying benefits.

The multi-step-in-one formula combines retinyl retinoate with stabilised vitamin C and hyaluronic acid for profound visible improvement in skin tone, texture and radiance.

r-Retinoate Day & Night interlaces revolutionary science with a sublime sensorial experience that's highly tolerated by the most sensitive skin.

*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93
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Reasons to shop Medik8

Free standard Delivery on orders over €50
15% off your first order
"No questions asked" easy 30 day returns
r-Retinoate® Intense
r-Retinoate® Intense
  • Rejuvenate
  • |
  • Firm
  • |
  • Brighten
 Intense Youth Activating Cream
Key Benefits
Accelerated Age-Defying Results, Day & Night

Uniquely photostable retinyl retinoate doesn't lose its power in sunlight so delivers visible illuminating, smoothing & revitalising benefits both morning & night.

3-in-1 Time-Saver

Delivers all the visible wrinkle-smoothing, brightening & hydrating benefits of vitamin A, vitamin C and hyaluronic acid in one luxurious formula.

8x Stronger Than Retinol

Medik8-exclusive encapsulated retinyl retinoate is proven to be gentle yet 8x more powerful than standard retinol* in delivering visible results.


*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

How to Use

First-time use

If you're new to r-Retinoate Day & Night we recommend a patch test at least 24 hours before first use. Learn how to patch test here.

Phase in application gradually. Use twice a week for the first 2 weeks, every other day/night for the next 2 weeks, then every daily.

Step 1

After cleansing, massage 2 pumps of r-Retinoate Day & Night evenly across face, neck and décolletage.

Step 2

Always use a sunscreen in the morning when using vitamin A. We recommend Advanced Day Ultimate Protect.

Uses Per Tube

120

Key Ingredients
Encapsulated Retinyl Retinoate

Patented and exclusive to Medik8, this unique vitamin A molecule is the breakthrough result of 8 years of expert research. Retinyl retinoate is proven to be 8x more powerful than classic retinol* in delivering astonishing age-defying results.

*H. Kim et al., Synthesis and in vitro biological activity of retinyl retinoate, a novel hybrid retinoid derivative, Bioorganic & Medicinal Chemistry, 2008, 15;16(12), pp 6387-93

7% Stabilised Vitamin C (tetrahexyldecyl ascorbate)

A low-irritation form of vitamin C that delivers exceptional antioxidant protection against harmful free radical damage while supporting collagen production for a visibly even, more youthful-looking complexion.

Multi-Weight Hyaluronic Acid

With the ability to attract and retain more than 1,000 times its own weight in water, multi-weight hyaluronic acid draws moisture into multiple layers of the skin; leaving the complexion deeply hydrated and visibly supple.

Vitamin E

A powerful antioxidant that provides additional antioxidant protection against the ageing effects of free radicals. It also helps to boost the power of vitamin C for optimum visible results.

Multi-Weight Hyaluronic Acid

With the ability to attract and retain more than 1,000 times its own weight in water, multi-weight hyaluronic acid draws moisture into multiple layers of the skin; leaving the complexion deeply hydrated and visibly supple.

Vitamin E

A powerful antioxidant that provides additional antioxidant protection against the ageing effects of free radicals. It also helps to boost the power of vitamin C for optimum visible results.

Full List of Ingredients
r-Retinoate® Day & Night
Youth Activating Cream

INGREDIENTS

Aqua (Water), Tetrahexyldecyl Ascorbate, Heptyl Undecylenate, Caprylic/Capric Triglyceride, Methylpropanediol, Polylactic Acid, Cetearyl Olivate, Sodium Polyacryloyldimethyl Taurate, Cetearyl Isononanoate, Distarch Phosphate, Tocopheryl Acetate, Sorbitan Olivate, Hydrogenated Polydecene, Retinyl Retinoate, Glycerin, Caprylyl Glycol, Sodium Hyaluronate, Cholesteryl Nonanoate, Disodium EDTA, Hydroxyacetophenone, Canola Oil, Cetearyl Alcohol, Phenylpropanol, Vanilla Planifolia (Vanilla) Fruit Extract, 3-O-Ethyl Ascorbic Acid, Sodium Metabisulfite, BHT, Sodium Hydroxide, Trideceth-10.

PRECAUTIONS

Avoid eye contact. If product enters eyes, rinse well with water. If irritation occurs, cease use. Should irritation persist, consult a doctor. Use only as directed. Do not apply to damaged or inflamed skin. Contains vitamin A that may increase skin’s sensitivity to the sun. Avoid sun exposure and wear sunscreen during the day while using this product and for a week afterwards. Use with caution if taking dietary supplements or using other products containing vitamin A/retinoids. Consult a doctor if pregnant or breastfeeding before use. Patch testing prior to use is advised. Refer to medik8.co/patch for an in-depth guide to patch testing.

*Although we try our best to ensure this list of ingredients is accurate there may be product upgrades from time to time, or slight variants between different regions based on local laws, meaning the only definitive ingredient list is that which is printed on the product packaging.
  • No artificial fragrance
  • No synthetic colours
  • Paraben free
  • Alcohol free
Experts Recommended

Combines vitamin A & vitamin C power in one luxurious age-defying serum.

Daniel Isaacs
Chief Product Officer

It’s easy to see why this moisturiser counts Hailey Bieber as one of its fans!

TRACY ACHONWA
Beauty Writer - British Vogue

Complete Your Regime

Reviews

Frequently Asked Questions

Can I use r-Retinoate Day & Night if I'm pregnant or breastfeeding?
As a cosmetics company, we are unable to provide product advice in relation to medical conditions such as pregnancy or breastfeeding. We strongly recommend discussing the ingredients with your GP or midwife before use. We do, however, generally recommend avoiding vitamin A use while pregnant or breastfeeding, which is why we offer a plant-based vitamin A alternative - Bakuchiol Peptides.
How and when should I apply r-Retinoate Day & Night?
r-Retinoate Day & Night can be applied both day and night. After cleansing, massage 2 pumps evenly across the face, neck and décolletage.
At what age can I start to use this product?
All of our products are suitable for those aged 16+ - including r-Retinoate Day & Night.
Do I need to use a moisturiser on top of r-Retinoate Day & Night?
We would recommend using a moisturiser on top of r-Retinoate Day & Night as this formula is a creamy-textured serum, designed to be layered under a moisturiser morning and/or night.
What’s the difference between r-Retinoate Day & Night and r-Retinoate Intense?
r-Retinoate Day & Night is formulated with retinyl retinoate, a unique form of vitamin A that’s photostable (meaning it doesn’t lose its power when exposed to sunlight). This means it’s a vitamin A formula that can be used both morning and night for accelerated age-defying results. r-Retinoate Intense is a 5-in-1 night cream and the jewel in the Medik8 vitamin A crown. Combining 5 of Medik8's most advanced age-defying technologies in 1 extraordinary nighttime cream (retinyl retinoate, retinal, ceramides, peptides and hyaluronic acid), it delivers everything your skin needs for astonishing youth-renewing results in one simple but luxurious step. Remember; r-Retinoate Intense can only be used in the evening due to it containing retinal (which is not photostable).
r-Retinoate® Day & Night